Martín J. Lavecchia

Doctor en Química
Profesor Adjunto UNLP
Investigador Adjunto de CONICET
 

 


Formación de Recursos Humanos

Co-Director de:

  • Patricia Quispe (Becaria CONICET)
  • Leandro Martínez Heredia (Becario CONICET - INIFTA)

 

Co-Director de Tesis de:

  • Julián Fernández (UBA)

 


Publicaciones

Año 2021
  • L. M. Balsa, V. Ferraresi-Curotto, M. J. Lavecchia, G. A. Echeverría, O. E. Piro, J. García-Tojal, R. Pis-Diez, A. C. González-Baró, I. E. León.
    Anticancer activity of a new copper(II) complex with a hydrazone ligand. Structural and spectroscopic characterization, computational simulations and cell mechanistic studies on 2D and 3D breast cancer cell models. Dalton Transactions, 50(28), 9812-9826, 2021. DOI: 10.1039/D1DT00869B
  • M. R. Rodríguez, M. J.Lavecchia, B. S.Parajón-Costa, A. C. González-Baró, María R. González-Baró, E. R. Cattáneo.
    DNA cleavage mechanism by metal complexes of Cu(II), Zn(II) and VO(IV) with a schiff-base ligand. Biochimie, 186, 43-50, 2021. DOI: 10.1016/j.biochi.2021.04.002
Año 2020
  • L. M. Balsa, P. Quispe, E. J. Baran, M. J. Lavecchia, I. E. León.
    In silico and in vitro analysis of FAK/MMP signaling axis inhibition by VO-clioquinol in 2D and 3D human osteosarcoma cancer cells. Metallomics, 2020, 12, 1931-1931. DOI: 10.1039/D0MT00176G
  • J. F. Fernández, M. J. Lavecchia. Small molecule stabilization of non-native protein-protein interactions of SARS-CoV-2 N protein as a mechanism of action against COVID-19. Journal of Biomolecular Structure and Dynamics, 2020 DOI: 10.1080/07391102.2020.1860828
Año 2019
  • P. A. Quispe, M. J. Lavecchia, Ignacio E. León. On the discovery of a potential survivin inhibitor combining computational tools and cytotoxicity studies. Heliyon, 2019, 5, e02238. DOI: 10.1016/j.heliyon.2019.e02238
Año 2016
  • M. J. Lavecchia, R. Puig de la Bellacasa, J. I. Borrell, C. N. Cavasotto. Investigating molecular dynamics-guided lead optimization of EGFR inhibitors. Bioorganic & Medicinal Chemistry, 2016, 24, 768-778. DOI: 10.1016/j.bmc.2015.12.046
Año 2015
  • N. Urquiza, M. S. Islas, S. T. Ariza, N. Jori, J. J. Martínez Medina, M. J. Lavecchia, L. L. López Tévez, L. Lezama, T. Rojo, P.A.M. Williams, E. G. Ferrer. Anti-thyroid and antifungal activities, BSA interaction and acid phosphatase inhibition of methimazole copper(II) complexes. Chemico-Biological Interactions, 2015, n° 229, 64-72. DOI: 10.1016/j.cbi.2014.12.036
  • M. J. Lavecchia, R. P. De La Bellacasa, J. I. Borrell, C. N. Cavasotto. Investigating molecular dynamics-guided lead optimization of EGFR inhibitors. Bioorganic & medicinal chemistry, 2015, 24, n° 1465, 768-778. DOI: 10.1016/j.bmc.2015.12.046