Evelina G. Ferrer

Doctora en Química
Profesora Adjunta UNLP
Investigadora Principal de CONICET
 


Formación de Recursos Humanos

Director de:


Publicaciones

Año 2019
  • J. E. Parente, L. G. Naso, K. Jori, C. A. Franca, A. M. da Costa Ferreira, P. A. M. Williams, E. G. Ferrer.
    In vitro experiments and infrared spectroscopy analysis of acid and alkaline phosphatase inhibition by vanadium complexes.
    New Journal of Chemistry, 2019, Advance Article. DOI: 10.1039/C9NJ01638D
  • H. Goitia, P. A. Quispe, L. G. Naso, V. Martínez, M. Rey, A. Rizzi, E. G. Ferrer, P. A. M. Williams.
    Interactions of rutin with the oxidovanadium(IV) cation. Anticancer improvement effects of glycosylated flavonoids. New Journal of Chemistry, 2019, Advance Article. DOI: 10.1039/C9NJ01039D
  • N. Martini, J. E. Parente, F. D’Alessandro, M. Rey, A. Rizzi, P. A. M. Williams, E. G. Ferrer.
    Potential bio-protective effect of copper compounds: mimicking SOD and peroxidases enzymes and inhibiting acid phosphatase as a target for anti-osteoporotic chemotherapeutics. Molecular Biology Reports, 2019, 46, 867–885. DOI: 10.1007/s11033-018-4542-8
  • J. J. Martínez Medina; L. G Naso; A. L. Pérez; A. Rizzi; N. Okulik; M. Valcarcel; C. Salado; E. G. Ferrer; P. A. M. Williams.
    Synthesis, characterization, theoretical studies and biological (antioxidant, anticancer, toxicity and neuroprotective) determinations of a copper(II) complex with 5-hydroxytryptophan. Biomedicine and Pharmacotherapy, 2019, 111, 414-426. DOI: 10.1016/j.biopha.2018.12.098
  • J. J. Martínez Medina, E. G. Ferrer, P. A. M. Williams, N. B. Okulik.
    Theoretical/experimental investigation and antimutagenic effect of the oxidovanadium(IV) baicalin coordination complex. Inorganica Chimica Acta, 2019, 487, 369-378. DOI: 10.1016/j.ica.2018.12.042
  • N. Jori, P. A. Quispe, M. S. Islas, O. E. Piro, G. A. Echeverría, E. G. Ferrer, P. A. M. Williams.
    Unexpected oxidation of nitrendipine. Properties of oxidized nitrendipine and its Cu(II) complex. Journal of Molecular Structure, 2019, 1177, 199-203. DOI: 10.1016/j.molstruc.2018.09.065
  • J. E. Parente, P. A. M. Williams, E. G. Ferrer.
    Vanadium Compounds as Biocatalyst Models. Biological Trace Element Research, 2019, 1-7. DOI: 10.1007/s12011-019-01874-5
Año 2018
  • V. R. Martínez, M. V. Aguirre, J. S. Todaro, O. E. Piro, G. Etcheverría; E. G. Ferrer, P. A. M. Williams. Azilsartan and its Zn(II) complex. Synthesis, anticancer mechanisms of action and binding to bovine serum albumin. Toxicology in Vitro, 2018, 48, 205-220. DOI: 10.1016/j.tiv.2018.01.009
  • M. S. Islas, J. J. Martínez Medina, O. E. Piro, G. Etcheverría, E. G. Ferrer, P. A. M. Williams. Comparisons of the spectroscopic and microbiological activities among coumarin-3-carboxylate, o-phenanthroline and zinc(II) complexes. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2018, 198, 212-221. DOI: 10.1016/j.saa.2018.03.003
  • V. R. Martínez, M. V. Aguirre, J. S. Todaro, O. E. Piro, G. A. Echeverría, L. G. Naso, E. G. Ferrer, P. A. M. Williams. Interaction of Zn with Losartan. Activation of Intrinsic Apoptotic Signaling Pathway in Lung Cancer Cells and Effects on Alkaline and Acid Phosphatases. Biological Trace Element Research, 2018, 186, 413-429. DOI: 10.1007/s12011-018-1334-x
  • E. G. Ferrer. Nuevas estrategias de la Química Farmacéutica para el desarrollo de compuestos antidepresivos. SAFYBI, 2018, 160, 26-30. ISSN 0558-1265 | Acceso: RI CONICET Digital | Texto completo: PDF (16 MB)
Año 2017
  • J. J. Martínez Medina, L.G. Naso, A. L. Pérez, A. Rizzi, E.G. Ferrer, P.A.M Williams. Antioxidant and anticancer effects and bioavailability studies of the flavonoid baicalin and its oxidovanadium(IV)complex. Journal of Inorganic Biochemistry, 2017, 166, 150-161. DOI: 10.1016/j.jinorgbio.2016.11.005
  • J. J. Martínez Medina, L. Naso, A.L. Pérez, A. Rizzi, N.B. Okulik, E.G. Ferrer, P. A. M Williams. Apigenin oxidovanadium(IV) cation interactions. Synthesis, spectral, bovine serum albumin binding, antioxidant andanticancer studies. Journal of Photochemistry and Photobiology A: Chemistry, 2017, 344, 84-100. DOI: 10.1016/j.jphotochem.2017.05.007
  • N. Martini, J.E. Parente, M.E. Toledo, G.E. Escudero, C.H. Laino, J.J. Martínez Medina, G.A. Echeverría, O.E. Piro, L. Lezama, P.A.M. Williams, E.G. Ferrer. Evidence of promising biological-pharmacological activities of the sertraline-based copper complex: (SerH2)2[CuCl4]. Journal of Inorganic Biochemistry, 2017,174, 76-89. DOI: 10.1016/j.jinorgbio.2017.05.012
  • J. J. Martínez Medina, E.G. Ferrer, P.A.M Williams, N. B. Okulik. Theoretical investigation of the conformational space of baicalin. Journal of Molecular Graphics and Modelling, 2017, 76, 181-191. DOI: 10.1016/j.jmgm.2017.07.007
  • G. E. Escudero, C. H. Laino, N. Martini, G. A. Echeverría, O. E. Piro, P. A. M Williams, E.G. Ferrer. Zn(II) Based Potential Drug Containing Sertraline as a Strong Antidepressant Agent. Annals of medicinal chemistry and research, 2017, 3, 1017, 1-11. ISSN: 2378-9336 |Acceso al texto completo (CONICET Digital RI)
Año 2016
  • J. J. Martínez Medina, L.G. Naso, A. L. Pérez, A. Rizzi, E.G. Ferrer, P.A.M. Williams. Antioxidant and anticancer effects and bioavailability studies of the flavonoid baicalin and its oxidovanadium(IV)complex. Journal of Inorganic Biochemistry, 2016, 166, 150-161. DOI: 10.1016/j.jinorgbio.2016.11.005
  • L.G. Naso, V.R. Martínez, L. Lezama, C. Salado, M. Valcarcel, E.G. Ferrer, P.A.M. Williams. Antioxidant, anticancer activities and mechanistic studies of the flavone glycoside diosmin and its oxidovanadium(IV) complex. Interactions with bovine serum albumin. Bioorganic & Medicinal Chemistry, 2016, 24, 4108-4119. DOI: 10.1016/j.bmc.2016.06.053
  • G. Escudero, N. Martini, K. Jori, N. Jori, N. R. Maresca, C. H. Laino, L.G. Naso, P.A.M. Williams; E.G. Ferrer. Biological activities of Zn(II)-S-methyl-cysteinecomplex as antiradical, inhibitor of acid phosphatase enzyme and in vivo antidepressant effects. Journal of Enzyme Inhibition and Medicinal Chemistry, 2016, 31, 1625-1631. DOI: 10.3109/14756366.2016.1160900
  • L. G. Naso, L. Lezama, M. Valcarcel, C. Salado, P. Villacé, D. Kortazar, E. G. Ferrer, P. A. M. Williams. Bovine serum albumin binding, antioxidant andanticancer properties of an oxidovanadium(IV) complex with luteolin. Journal of Inorganic Biochemistry, 2016, 167, 80-93. DOI: 10.1016/j.jinorgbio.2016.01.021
  • M. S. Islas, A. Luengo, C.A. Franca, M. Griera Merino, L. Calleros, M. Rodriguez Puyol, L. Lezama, E.G. Ferrer, P.A.M. Williams. Experimental and DFT characterization, antioxidant and anticancer activities of a Cu(II)-irbesartan complex: structure-antihypertensive activity relationships in Cu(II)-sartan complexes. Journal of Biological Inorganic Chemistry, 2016, 21, 851-863. DOI: 10.1007/s00775-016-1384-5
  • G. E. Escudero, C. H. Laino, G. A. Echeverría, O. E. Piro, N. Martini, A. Rodríguez, J. J. Martínez Medina, L. L. López Tévez, E. G. Ferrer, P. A. M. Williams. Improving the antidepressant action and the bioavailability of sertraline by co-crystallization with coumarin 3-carboxylate. Structural determination. Chemico-biological Interactions, 2016, 249, 46-55. DOI: 10.1016/j.cbi.2016.03.010
  • L.G. Naso, I. Badiola, J. Márquez Clavijo, M. Valcarcel; C. Salado; E. G. Ferrer, P. A. M. Williams. Inhibition of the metastatic progression of breast and colorectal cancer in vitro and in vivo in murine model by theoxidovanadium (IV) complex with luteolin. Bioorganic & Medicinal Chemistry, 2016, 24, 6004-6011. DOI: 10.1016/j.bmc.2016.09.058
  • N. M. Urquiza, L. G. Naso, J. J. Martínez Medina, M. A. Moyano, L. Lezama, E. G. Ferrer, P. A. M. Williams. Pharmacological activities of propylthiouracil compound structurally modifiedby coordination with copper(II). Journal of Coordination Chemistry, 2016, 69, 1293-1312. DOI: 10.1080/00958972.2016.1167885
Año 2015
  • N. Urquiza, M. S. Islas, S. T. Ariza, N. Jori, J. J. Martínez Medina, M. J. Lavecchia, L. L. López Tévez, L. Lezama, T. Rojo, P.A.M. Williams, E. G. Ferrer. Anti-thyroid and antifungal activities, BSA interaction and acid phosphatase inhibition of methimazole copper(II) complexes. Chemico-Biological Interactions, 2015, n° 229, 64-72. DOI: 10.1016/j.cbi.2014.12.036
  • J. J. Martínez Medina, C.A. Torres, W. Alegre, C.A. Franca, L.L. López Tévez, E. G. Ferrer, N.B. Okulik, P.A.M. Williams. DFT vibrational assignments, in vitro antifungal activity, genotoxic and acute toxicity determinations of the [Zn(phen)2(cnge)(H2O)](NO3)2·H2O complex. Journal of molecular structure, 2015, 1100, 366-375. DOI: 10.1016/j.molstruc.2015.07.061
  • M. S. Islas, L. G. Naso, L. Lezama, M. Valcarcel, C. Salado, M. Roura-ferrer, E. G. Ferrer, P.A.M. Williams. Insights into the mechanisms underlying the antitumor activity of an oxidovanadium(IV) compound with the antioxidant naringenin. Albumin binding studies. Journal of inorganic biochemistry, 2015, 149, 12-24. DOI: 10.1016/j.jinorgbio.2015.04.011
Año 2014
  • M. S. Islas, J. J. Martínez Medina, L. L. López Tévez, T. Rojo, L. Lezama, M. Griera Merino, L. Calleros, M. A. Cortés, M. Rodriguez Puyol, G. A. Echeverría, O. Piro, E.G. Ferrer, P.A.M. Williams. Antitumoral, Antihypertensive, Antimicrobial and Antioxidant Effects of an Octanuclear Copper(II)-Telmisartan Complex with an Hydrophobic Nanometer Hole. Inorganic Chemistry, 2014, 53, n° 11, 5724-5737. DOI: 10.1021/ic500483p
  • J. J. Martínez Medina, L. L. López Tévez, N. B. Okulik, M. S. Islas, E.G. Ferrer, P.A.M. Williams. Copper(II) complexes with cyanoguanidine and o-phenanthroline: Theoretical studies, in vitro antimicrobial activity and alkaline phosphatase inhibitory effect. Journal of Molecular Structure, 2014, 1058, 298-307. DOI: 10.1016/j.molstruc.2013.11.014
  • N. Urquiza, M. S. Islas, M. L. Dittler, M. A. Moyano, S. G. Manca, L. Lezama, T. Rojo, J. J. Martínez Medina, M. Diez, L. L. López Tévez, P.A.M. Williams, E.G. Ferrer. Inhibition behavior on alkaline phosphatase activity, antibacterial and antioxidant activities of ternary methimazole-phenanthroline-copper(II) complex. Inorganica Chimica Acta, 2014,1058, 298-307. DOI: 10.1016/j.ica.2013.05.022
  • M. J. Correa, E. Ferrer, M. C. Añon, C. Ferrero. Interaction of modified celluloses and pectins with gluten proteins. Food hydrocolloids, 2014, 35, 91-99. DOI: 10.1016/j.foodhyd.2013.04.020
  • L. Naso, M. Valcarcel Cuesta, M. Roura-Ferrer, D. Kortazar, C. Salado, L. Lezama, T. Rojo, A. C. González Baro, P. A. M. Williams, E.G. Ferrer. Promising antioxidant and anticancer (human breast cancer) oxidovanadium(IV) complex of chlorogenic acid. Synthesis, characterization and spectroscopic examination on the transport mechanism with bovine serum albumin. Journal of Inorganic Biochemistry, 2014, 135, 86-9.DOI: 10.1016/j.jinorgbio.2014.02.013
  • L. Naso, M. Valcarcel, P. Villacé, M. Roura-Ferrer, C. Salado, E.G. Ferrer, P.A.M. Williams. Specific antitumor activities of natural and oxovanadium(IV) complexed flavonoids on human breast cancer cells. New Journal of Chemistry, 2014, 38, 2414-2421. DOI: 10.1039/c3nj01649h